Brothers & Sisters premiered on ABC on April 28, 2007. As kids, brothers and sisters share many laughs, work through many arguments and form many bonds. As adults the same rules apply but it gets a lot more complicated when they've all grown into very different people... united by a gene pool. The adult children of Henry Walker, along with their respective families, have gathered to celebrate a birthday. What they don't know is that tonight the patriarch will die. With this safety net gone, everyone will be forced to face the reality of their lives. Kitty's radio success has led to a TV pundit job in Los Angeles, but her New York boyfriend just proposed. Charlie and Nora can't work with each other but somehow they have to in order to save the family business. Kevin's well ordered life is shaken by the news his ex-wife is moving his 12-year-old son to Texas. Justin's kicked nicotine but other addictions and his gulf war distress keep him from moving forward. The challenges of an autistic son are pushing Nora to the breaking point. Set in Los Angeles, this multi-generational family works to balance their personal lives with the family business, their siblings, and a grieving mother.